Future studies should assess the long-term efficacy and safety of peppermint oil and its efficacy relative to other IBS treatments including antidepressants and antispasmodic drugs. Peppermint oil is a safe and effective short-term treatment for IBS. The most commonly reported adverse event was heartburn. Although peppermint oil patients were significantly more likely to experience an adverse event, such events were mild and transient in nature. Peppermint oil was found to be significantly superior to placebo for global improvement of IBS symptoms (5 studies, 392 patients, relative risk 2.23 95% confidence interval, 1.78-2.81) and improvement in abdominal pain (5 studies, 357 patients, relative risk 2.14 95% confidence interval, 1.64-2.79). The risk of bias was low for most of the factors assessed. Nine studies that evaluated 726 patients were identified. It may also reduce other symptoms like light sensitivity, nausea, and vomiting. Some small studies show it can lessen the pain of migraine headaches. Some research has suggested that the oils in peppermint may have a number of other health benefits, such as fresher breath, better digestion, and reduced pain from headaches. Outcomes were analyzed using an intention-to-treat approach. The active ingredient in peppermint is menthol. Outcomes included global improvement of IBS symptoms, improvement in abdominal pain, and adverse events. Study quality was evaluated using the Cochrane risk of bias tool. Protects from Sun- burn and Sun- tan Health benefits of Peppermint Tea for Weight Loss 6. A literature search upto February 2013 identified all applicable randomized-controlled trials. Anti-inflammatory, Antiseptic and Astringent properties 2. Cross-over studies that provided outcome data before the first cross-over were included. Randomized placebo-controlled trials with a minimum treatment duration of 2 weeks were considered for inclusion. Medical interventions are limited and the focus is on symptom control. IBS is a common disorder that is often encountered in clinical practice. The aim of this study was to assess the efficacy and safety of enteric-coated peppermint oil capsules compared with placebo for the treatment of active irritable bowel syndrome (IBS).
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